CHEM 32002 BIOCHEMISTRY I - Spring 2017


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Syllabus
Template for summary


OBJECTIVES
The objectives of the course are for students to become familiar with structures of amino acids, proteins, nucleic acids, carbohydrates, and membranes. Students will learn about protein structure, protein function, protein evolution, protein regulation, DNA/RNA structure, and metabolism including glycolysis, citric acid cycle and oxidative phosphorylation.

REQUIREMENTS
A strong understanding of chemistry, in particular organic chemistry, is required. The use of a computer is highly encouraged, as protein structures will be studied in detail using freely available software.

GRADING
Grades from all four exams will be given numerical scores between 0-100; these will be converted into letter grades on a standard scale of:
97-100: A+; 93-96: A; 90-92: A-
87-89: B+; 83-86: B; 80-82: B-
77-79: C+; 73-76: C; 70-72:C-
69-60: D
59 or lower: F
Note that these cutoffs will apply to any exam with a mean of 73 or higher; for exams with means below 73, I will add a uniform amount to all exam scores sufficient to bring the mean up to 73. Your final grades for the semester will be calculated by summing the numerical scores for each of the four exams, adding any additional credit (as noted above), dividing by 4, and converting these into a final semester letter grade on the scale above.

EXTRA-CREDIT
Write a short review of an article that has appeared in either the scientific (Nature, Science etc.) or the popular literature (New York Times, The Economist, Scientific American etc.) describing some aspect of biochemistry (up to 25 points). Articles chosen should have appeared no earlier than January 1, 2014 and should be cleared with me ahead of time. Please use the template that appears on the website and email it to rghose@ghoselab.org. This summary should be emailed to me prior to the third examination.


LECTURE NOTES
Lecture 0
Lectures 1-2
Lectures 3-4
Lectures 5-6


CLASS HOURS
Mondays and Wednesdays
9:30-10:45 AM (MR-4)

OFFICE HOURS
Wednesdays
10:50 - 11:50 AM (MR-1219)
Also by appointment

TEXTBOOK
Lehninger, Nelson, and Cox, Principles of Biochemistry, 5th edition, Worth Publishing, 2008

ANNOUNCEMENTS
The class will meet in MR-4 from now on.